Indian Startup OrthoGraft Secures Funding for Innovative Wound Care Solutions
In a significant boost for tissue engineering in India, the Technology Development Board (TDB) of the Department of Science & Technology has announced financial assistance to OrthoGraft Pvt. Ltd., a medical device startup based in Vadodara, Gujarat. This funding will support the project titled ‘Production Set-up for Advanced Tissue Derived Biological Dressings,’ aimed at developing indigenous biological dressings for challenging clinical wound-care applications, including chronic wounds, diabetic foot ulcers, and burns.
OrthoGraft is recognized by the Department for Promotion of Industry and Internal Trade (DPIIT) and specializes in crafting tissue substitutes that cater to clinical reconstruction and functional repairs. The company utilizes proprietary technologies to process viable human tissue into shelf-stable substitutes while ensuring the retention of crucial biological and structural characteristics that are vital for effective wound healing.
Innovative Tissue Processing Methodology
Central to the project is a groundbreaking tissue-processing methodology developed to effectively remove cellular components while maintaining high tissue quality and preserving essential bioactive substances. The biological dressings produced from this process are designed to feature enhanced tensile strength and optimal Moisture Vapour Transmission Rate (MVTR), making them comparable to existing moist wound dressings on the market.
Building Manufacturing Capabilities
With the TDB’s backing, OrthoGraft plans to expand its production infrastructure at the Savli Technology Business Incubator in Vadodara, where a bio-incubation facility has already been leased. This facility offers valuable access to biotechnology research and development infrastructure necessary for the advancement of medical devices. The startup has successfully acquired the necessary licenses from the Central Drugs Standard Control Organization (CDSCO) for the manufacturing of medical devices for testing, and is actively pursuing partnerships with tertiary-care hospitals and medical institutions to foster further development and clinical application of its technology.
Collaborative Efforts for Innovation
OrthoGraft has cultivated extensive expertise in tissue processing and currently holds two granted patents in the United States. The company is collaborating with esteemed institutions, including IIT Ropar and various multispecialty hospitals, to refine and enhance its technology platform. Previously, OrthoGraft has participated as an industry startup partner in multi-institutional research and development projects supported by the Government of India.
Support for Indian Innovations
During the announcement, Shri Rajesh Kumar Pathak, Secretary of TDB, emphasized the importance of advanced biomaterials and tissue-engineered products for India’s medical technology ecosystem. He stated that the strategic support provided to OrthoGraft aims to transform its tissue-processing expertise into commercially viable wound-care products, thereby bolstering India’s capabilities in advanced healthcare materials and creating pathways for Indian innovations to thrive in global markets.
Expressing gratitude for the TDB’s assistance, OrthoGraft’s leadership remarked that this funding will not only allow the company to build dedicated production capabilities but also accelerate the translation of its innovative tissue-processing platform into high-quality biological wound-care solutions. The ultimate goal is to expand the availability of advanced tissue substitutes in the Indian market, enhancing patient care and outcomes.
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